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Wildlife Toxicity Reference Values (TRVs)

for Ecological Risk Assessments

An integral component of a wildlife ecological risk assessment (ERA) is the development of some quantitative measure of the toxicity of a chemical to the animals of concern. This measure is often referred to as a toxicity reference value, or TRV. Our Center has developed, and is implementing, a standard method for developing toxicological profiles and toxicity reference values for military-related substances that may potentially pose risks to wildlife. Our Technical Guide 254 provides the standard practice for the development and documentation of wildlife TRVs. It is written primarily for risk assessors. The Standard Practice can be downloaded by clicking on the icon below.

TG 254

Standard Practice for Wildlife Toxicity Reference Values



October  2000 1.69 MB


Our Center's Wildlife Toxicity Assessment (WTA) program is implementing this Standard Practice for environmental chemicals of military concern. The Standard Practice is primarily intended for use by this Center to generate wildlife TRVs that are defensible and to provide a standard set of information for practitioners in the field. If a TRV relevant to a particular Army ERA has been generated by this Center using this methodology, then its use is expected unless an alternative can be reasonably defended. This Center is implementing this program in a phased approach, focusing upon the highest priority chemicals first. Other U.S. Army and military entities are encouraged to use this Standard Practice and our WTA reports within their ERA programs.

The following Wildlife Toxicity Assessment reports are available for use or in preparation.

Substance(s) CASRN Revision No. Date Status File Size File Icon
Acetylene 74-86-2 1 Jan 2006 Final 83KB
Aldrin 309-00-2 1 Dec 2005 Final 201KB
Amino-DNTs 35572-78-2
1 (rev 2 in progress) Dec 2005 Draft 124KB
Benzo-a-pyrene 50-32-8 1 (rev 2 in progress) Dec 2005 Final 156KB
Chlordane 12789-03-6 1 Dec 2005 Final 234KB
Dinitrobenzene 99-65-0 1 Dec 2001 Final 182KB
Dinitrotoluenes 121-14-2
1 (rev 2 in progress) Jan 2006 Final 275KB
Ethylene 74-85-1
  April 2009 Final 520KB
Hexachlorocyclohexane 74-85-1
1 Jan 2006 Final 119KB
Nitrodiphenylamines 119-75-5
1 Apr 2006 Final 161KB
Nitroglycerin 55-63-0 2 Nov 2007 Final 165KB
Perchlorate 7790-98-9
1 Feb 2007 Final 448KB
PETN 78-11-5 1 (rev 2 in progress) Nov 2001 Final 126KB
Phenanthrene 85-01-8 1 Jan 2006 Final 102KB
Picric Acid 88-89-1 1 Aug 2005 Final 131KB
Propylene 115-07-1 1 Jun 2004 Final 131KB
Thallium 7440-28-0 1 Dec 2007 Final 202KB
Trinitrobenzene 99-35-4 1 Nov 2001 Final 234KB
Trinitrotoluene (TNT) 118-96-7 1 (rev 2 in progress) Nov 2001 Final 234KB
RDX 121-82-4 1 (rev 2 in progress) July 2002 Final 234KB
HMX 2691-41-0 1 (rev 2 in progress) Nov 2001 Draft 153KB
Hexachlorocyclohexane 608-73-1 In progress        
Tetryl 479-45-8 1 Jul Draft 134kb  
Phenol 108-95-2 Final      
Nitroguanidine 556-88-7 In progress        
Nitrocellulose 9004-70-0 In progress        
Thiodiglycol 111-48-8 Final        
White phosphorus 7723-14-0 In progress        


The Army Surgeon General is responsible for providing policy and technical expertise on human health and ecological aspects of pollution resulting from Army activities and operations (Army Regulation (AR) 200-1 Environmental Protection and Enhancement and AR 40-5 Preventive Medicine). The Army Surgeon General has delegated this responsibility through the U.S. Army Medical Command to the U.S. Army Center for Health Promotion and Preventive Medicine. This guide was developed pursuant to this authority.

This technical guide and the associated wildlife toxicity assessment reports should not be construed as official Department of the Army policy unless so designated by other authorizing documents. This document provides guidance and technical reference material based on scientific information current at the time of publication. As available information and supporting data are continuously being advanced, users are cautioned to ascertain existence of any updated information.

Point of Contact

E-mail HERP



These Wildlife Toxicity Assessments were developed with resources from the following organizations: US Air Force Institute for Environment, Safety, and Occupational Health Risk Analysis, U.S. Army Environmental Center, Defense Environmental Restoration Program