A Toxicity Clearance involves a toxicological evaluation of
materials prior to introduction into the Army supply system. The program
manager is responsible for identifying technically feasible materials and
requesting a Toxicity Clearance for use of that material within their program.
Army Regulation 40-5 promulgates the Toxicity Clearance process in the Army.
The Department of the Army (DA) Pamphlet 70-3 requires a Toxicity Clearance
(approval) prior to use of a new material or chemical. USAPHC
toxicity evaluations require the following information:
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final chemical formulation (handled as proprietary information if required)
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identity and application of new material; identity of material being replaced,
if applicable
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reports from manufacturers pertaining to commercial use of the product in the
marketplace and material safety data sheets (MSDSs)
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available human and animal toxicity study and epidemiology information
A toxicity evaluation is performed and clearances are
approved based on the specific product application or use condition.
USAPHC
is currently evaluating replacement materials for such items as fire
suppressants, solvents, refrigerants, fabric finishes, and protective clothing.
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